With the antiasthmatic action of Chinese herbal medicine has ?Ephedra :containing a variety of alkaloids ,mainly for ephedrine ,total biological alkali content 80%~ 85% ,followed by pseudoephedrine and ephedrine ,pseudoephedrine, trace ,methyl norephedrine ,still containing volatile benzyl methylamine ,catechol tannins and a small amount of volatile oil, oil containing a – terpineol .
Taste :Xin ,was swept by the micro ,temperature .And lung ,bladder. Action :sweating ,asthma ,and water .Ephedrine on Zhi Qiguan smooth muscle relaxation. On spasticity Zhi Qiguan has obvious spasmolytic effect .
These effects and can promote the sympathetic nerve endings release norepinephrine and direct effects on adrenergic receptor. Methyl ephedrine and pseudoephedrine and ephedrine on the smooth muscle of the spasmolytic effect similar to ,but smaller effects on blood pressure .
Ephedrine excitable myocardial and contraction of blood vessels ,the heart and blood vessels have a similar role of adrenergic ,can make the heartbeat is accelerated ,strengthen blood vessels vasoconstriction ,increased blood pressure ,but the role of the weak .
Persistent diastolic blood vessels ,and the role was very little. Therefore ,for intranasal ,without secondary blood vessels dilated .Larger treatment volume of ephedrine can excitability of the cerebral cortex and subcortical central ,Cause mental excitement ,insomnia ,restlessness ,tremor .
Also can be excited the respiratory and blood vessels central motor .When the medulla suppressed ,ephedrine has come to effect .A short time continuous and repeated application of ephedrine ,can make the function of rapidly weakened ,finally can be completely ineffective ,deactivated after hours of Ephedra volatile oil can be recovered .
In vitro on influenza virus has a strong inhibition ,and prove to infection with influenza A virus PRg strain of mice have a certain effect. Adverse reactions :ephedra commonly used in transpiration of antiasthmatic ,overdose, often occur trouble Zao ,insomnia and other CNS symptoms ,and elevated blood pressure and other side effects.
With hypertension ,coronary insufficiency ,arteriosclerosis ,hyperthyroidism ,diabetes mellitus ,insomnia with caution or hanged. Cinnamomum camphor oil composition :mainly containing eucalyptol ,linalool and camphor ,followed by B – pinene and terpineol .
One of eucalyptol ,linalool and terpineol are antiasthmatic effects. Taste :sweep by temperature ,symplectic ,aroma ,non-toxic .Sweep lung. Action :effects of expelling wind and cold ,asthma ,regulating qi and activating blood circulation ,pain and itching .
Folk with camphor root ,camphor wood cold headache ,rheumatic pain, traumatic injury and Keshan disease ;with camphor tree child chronic arthritis research by Zhi Qiguan .Investigate discovery ,camphor tree child volatile oil has strong antiasthmatic effects ,clinical asthma effect is remarkable ,but the source of camphor camphor son as Ye Fengfu ,and the processing is more complex .
Cinnamomum camphor oil by pharmacological studies demonstrate ,its pharmacological effects and camphor tree seed oil is basic and same ,can relaxed Zhi Qiguan smooth muscle ,produce significant antiasthmatic effect ,at the same time there are some antitussive ,antiasthmatic expectorant effect.
The clinical curative effect ,expectorant ,antitussive effect is poor ,the emphysema complicated and serious illness effect is low. Suitable for treating arthritis and asthma in wheezy Zhi Qiguan Zhi Qiguan .
In 10 minutes after taking the drugeffect ,effect of maintenance for 3~ 10 hours.Adverse reactions :a small number of patients have nausea ,vomiting ,palpitation ,dizziness ,but were not serious ,disappear .
In volatile oil of Litsea cubeba oil constituents :main component of citral ,followed by limonene ,geraniol ,vanillin ,camphene ,methyl heptenone .Taste :sweep by symplectic ,spleen ,stomach ,and temperature .
The kidney ,bladder ,lung. Action :warming spleen and kidney ,Jianweixiaoshi .Recent study has the strong anti allergic effects of antiasthmatic ,guinea pig isolated tracheal smooth muscle .
Although experiments ,Litsea cubeba oil on normal gas pipe smooth muscle and histamine or acetylcholine induced contraction of smooth muscle relaxation effect Beforehand ,Litsea cubeba oil can be blocked by histamine or acetylcholine induced contraction ,effects were propranolol blockade.
On experimental asthma in guinea pigs ,by gavage ,intraperitoneal injection or inhalation administration has the protective function .More than 1000 casesclinical observation showed that: oral administration of Litsea cubeba oil on chronic gas pipe arthritis has a good effect, and can obviously improve the pulmonary ventilation function and spirometry.
Nasal suction therapy on asthma chronic inflammation and asthma Zhi Qiguan Zhi Qiguan has obvious and immediate antiasthmatic effect ,general 1 ~ 2minutes ofwork, maintain 30 minutes.Litsea cubeba oil gavage ,intraperitoneal injection or inhalation ,has expectorant effect .
Try and test show that ,Litsea cubeba oil on Staphylococcus grapes global bacterium ,Escherichia coli ,Shigella ,Salmonella typhi has strong bacteriostasis. Adverse reactions :Cases with oropharyngeal drying ,constipation ,stomach discomfort ,belching ,and dizziness.
Inhalation can be sneezing of irritation symptoms .Was licorice constituents :containing a variety of alkaloids ,including sophocarpine taste .Sweep :Gan ,was flat ,heart and lung ,spleen .
Sweep ,stomach. Role :Qingrejiedu ,lungs and cough, and asthma .Experiments show ,was licorice and was Gan antiasthmatic effect and mild alkali has no expectorant ,antitussive action, anti-inflammatory .
Using clinical asthma .A significant effect, is suitable for the treatment of Zhi Qiguan asthma and asthmatic chronic arthritis was Zhi Qiguan .Licorice hydrobromide injection by half an hour to work, maintain 2 ~ 6 hours.
Adverse reactions :small doses did not see its have ,large dosage on liver cells have a certain influence, therefore, patients with liver disease was ginseng components should be used with caution.
:containing matrine ,was was ginseng flavonoid and cytisine .Taste :cold ,was swept by the heart ,liver ,stomach .Sweep ,colorectal ,bladder. Action : Qingre dampness ,Qufeng insecticidal ,and asthma .
Proved was ginseng decoction and ginseng total alkali was the antiasthmatic action ,which was oxidized .Alkali and sophocarpine antiasthmatic effect was significant. Clinical use in the treatment of asthma in Zhi Qiguan have a certain effect .
Adverse reactions :a small number of patients have mild drowsiness .Inhalation medication on local stimulation, causing itching of the throat or cough .JiaoMu ingredients: contain volatile oils ,oil containing different anethole ,yak geraniol etc.
Taste :was swept by .,cold .And spleen ,bladder. Action :water ,relieving pain ,Zizania head .The antiasthmatic effect significantly antitussive ,expectorant effect ,not significant ,clinically applicable rule Zhi Qiguan asthmatic and wheezy Zhi Qiguan arthritis.
Oral effect quickly, after 5 ~ 10 minutes,role in the maintenance of about 6 hours.Adverse reactions :a few people have a head Dizzy ,nausea ,fever, flu. In ingredients: contains alkaloids ,flavonoids ,coumarins ,three terpene ,phenolic substances ,such as tannin .
Taste sweep by :flat ,acid ,was swept .Lung. Role :cough and asthma .Pharmacological experiment shows ,Elaeagnus on experimental chronic Zhi Qiguan arthritis has certain curative effect ,flavone parts have good antiasthmatic effects of clinically available in the treatment of asthma .
Zhi Qiguan Zhi Qiguan ,chronic arthritis. " by " ;spirit ;acupoint injection or inhalation of fast action when ,on asthmatic chronic inflammation in acute stage of attack Zhi Qiguan has good antiasthmatic effects.
Spray inhalation can be immediately seen ;point injection method after 15 minutes,can maintain 6 hours,the longest for up to 25 days .Adverse reactions :acupoint injection when people have an allergic reaction ,feeling chills and shivering .
Seven Ye Lian compositions :Goose long shoots contain volatile oils .Taste :temperature ,was swept by the sweeping ,Gan .Lung. Action :Shujin Huoluo ,swelling and pain .Experiments show ,the products of histamine and acetylcholine induced Zhi Qiguan spasm alleviate the effect of each type .
The clinical severity of different Zhi Qiguan asthma have a better effect ,especially for inhalant allergy induced asthma effect. Advantage is rapidder ,without epinephrine ,isoproterenol and Aminophylline and other common antiasthmatic drugs on cardiovascular and gastrointestinal side effects ;intramuscular and intravenous injection of aminophylline efficacy can be compared to some course ,lasting ,frequent asthma attacks ,common antiasthmatic drugs ineffective and the patient often worked well .
After 10 ~ 15minutesof intramuscular injection of onset ,25 ~30 minutesof effective, can maintain 3 ~ 6hours.Adverse reactions :intramuscular injection with mild acid feeling, individual sleepiness ,and sedation .
Juvenile red composition: three triterpenoid saponins part of Anti-asthmaic components ,mainly saponin II .Taste :sweep by temperature ,symplectic ,micro was .And lung. Effect of relieving cough ,activating blood and relieving pain :pharmacological .
The experiment proves ,juvenile red saponin has good antiasthmatic effects of mast cells ,have certain protective effect of clinical treatment of asthma .Zhi Qiguan effect is good ,the speed and intensity of asthma are better than aminophylline ,fewer adverse reactions and mild.
Oral usually after 15 ~ 60 minutesmore. Acetylated saponin on gastrointestinal irritation effect is smaller ,though the larger amount ,but the antiasthmatic effect superior to the juvenile red saponins.
Adverse reactions :some patients with dizziness ,dry mouth ,nausea. Juvenile red saponins on gastric mucosa have a certain irritation ,so it should take after meals .Gastric and duodenal ulcer activity period with caution .
Leaves Oil composition :argyi leaf oil is a multi-component mixture ,the isolation and identification, have been identified to have 7 kinds,namely: terpine enolase 4 ,B caryophyllene ,Artemisia alcohol ,linalool ,camphor ,borneol and eucalyptol .
Taste :sweep the was ,symplectic ,liver ,spleen ,and temperature .The kidney .Function :temperature by hemostasis ,dispelling cold and relieving pain .Found in recent years ,argyi leaf oil has antitussive ,expectorant ,anti-asthma effects .
0 5mg / ml blumea oil effect intensity and isoproterenol 0 125mg /ml. Whether oral or aerosol delivery ,can fight histamine or acetylcholine induced asthma attacks ,and lasting effect .
In guinea pigs with experimental show ,argyi leaf oil capable of inhibiting chemicals induced cough antitussive mechanism .Mainly inhibition of medullary cough central ,be Coramine offset.
Phenol red method show that ,in mice after oral or intraperitoneal injection of argyi leaf oil has expectorant effect .A blumea oil gavage ,on anaphylactic shock in guinea pigs has obvious protection role ,but aerosol delivery is invalid.
The mechanism may be inhibition of allergic mediator release ,or directly against allergic mediators ( histamine and slow reacting substance of anaphylaxis ) .Blumea oil could obviously inhibit the isolated toad heart contraction, the heart rate had little effect, but can be a cause of atrioventricular block .
The concentration increase can cause cardiac arrest .On Central nervous system has a sedative effect ,can make the rabbit activity is reduced. To mice ,can obviously prolong pentobarbital sodium sleep time.
In vitro experiments prove ,argyi leaf oil on earth bacteria and most gram-negative bacilli are inhibited. Adverse reactions :commonly used content without side effects ,only a few patients after oral administration of a dry throat ,nausea ,stomach discomfort ,such as dizziness reaction ,but without treatment can disappear .
Aerosol inhalation with local stimulation ,can cause choking. Lemongrass herb ingredients: fresh leaves and on the part of volatile oil containing 7%~ 1% ,oil containing Piperitone 40%~ 50% .
Taste :sweep the symplectic ,micro was ,temperature .And lung. Action :cough and asthma, inflammation and pain ,Qufeng Lishi .Clinical observations and pharmacological experiment ,Lemongrass herb preparations have asthma ,cough ,pain ,antidiuretic .
Hemostasis ,dredging ,anti-inflammatory ,vomiting and other effects, but with asthma as the strongest ,antidiuretic ,analgesic action time the other role ,once again ,but all have certain effect .
The lemon grass or pepper ketones on isolated intestinal smooth muscle of rabbit relax .Pepper ketones against barium chloride induced intestinal smooth muscle contraction ;also against hair fruit rue alkali on intestinal smooth muscle excitatory effects ;rue oil and pepper ketones on histamine induced Dolphin Zhi Qiguan rat spasm has obvious spasmolytic effects .
Clinical application to relieve asthma symptoms ,against Zhi Qiguan spasm .By stimulation in the guinea pig superior laryngeal nerve experimental proof ,this product has a certain effect on relieving cough and pepper ketones .
Rue oil and oil of main active ingredient in Pepper ketones ,on Staphylococcus aureus pneumonia bacteria ,double cones ,eight stacked cones bacteria a variety of bacteria have different degrees of inhibition .
Adverse reactions :rue grass without side effects ,more safety .Oral rue oil and pepper ketones may have nausea ,vomiting ,abdominal discomfort and other gastrointestinal reactions ,there are a few sore gums and epistaxis .
Oral sodium sulfite Piperitone no gastrointestinal reactions ,but can appear headache ,dizziness ,palpitations ,fatigue and so on. Aerosol on Zhi Qiguan have a local irritation ,few patients had a cough .
Earthworm composition containing :quality ,sodium succinate ,fatty acids ,cholesterol ,choline ,amino acids and earthworm ,earthworm antipyretic primes .Taste sweep by :salty ,cold ,and liver .
Spleen ,bladder. Action :clearing away heat and calming wind ,relieving asthma ,Tongluo ,diuresis. By earthworm to nitrogen containing effective components of mice and rabbit isolated-lung perfusion is a significant Zhi Qiguan diastolic function.
To advance after histamine or hairy fruit rue alkali treatment of the perfused lung Zhi Qiguan diastolic function. On histamine induced asthma in guinea pig spray protective effects induced by histamine .
Zhi Qiguan spasm ,produce better clinical application in the treatment of asthma .Zhi Qiguan asthma and allergic asthma ,especially suitable for hot asthma patients. Pheretima effective components of sodium succinate has a wide chest ,phlegm ,relieving asthma effect.
Its diastolic Zhi Qiguan smooth muscle of slow and protracted ,clinical apply Zhi Qiguan asthma .Sodium succinate and promethazine ( phenergan Qin ) composed of tulobuterol tablets ,on allergic asthma ,asthma and Zhi Qiguan long-term taking ephedrine ,aminophylline have adverse reactions or invalid patients with good results, after the clothes can increase appetite ,promote sleep .
For inflammatory or other diseases caused by asthma ,less effects ,preferably with anti-inflammatory drugs with use. Adverse reactions, injection can cause localized urticaria and anaphylaxis.